Most supplement brands tell you their ingredients are tested. We show you the actual results — purity percentages, heavy metal readings, microbiology counts, and the batch numbers you can trace. If a result is unusual, we flag it and explain it. No hiding behind "quality assured" language.
5
ACTIVE INGREDIENTS
5
COAS PUBLISHED
USP
TESTING STANDARD
// Our Transparency Standard
These are the actual Certificates of Analysis from our raw ingredient supplier, Shaanxi Fairir Biotech Co., Ltd (China). Each COA is issued by the supplier's quality control department and verified by HPLC assay, ICP-MS heavy metal testing, GC-MS solvent screening, and USP-method microbiological testing. We publish them unedited — including the one result that falls outside specification, which we explain in full below. A supplement company that only shows you passing results is not showing you everything.#1 — SENOLYTIC
Cotinus coggygria (Smokebush) — Stem extract
BATCH NO.
FH20260106
MANUFACTURE DATE
Jan 06, 2026
BATCH QUANTITY
280 kg
EXPIRY DATE
Jan 05, 2029
Purity & Identity
Physical
Heavy Metals (ICP-MS)
Mercury (Hg)
Not detected
Lead (Pb)
0.40 mg/kg
Arsenic (As)
0.42 mg/kg
Microbiological (USP <61> / <62>)
E. coli
Not detected
Salmonella
Not detected
Staphylococcus
Not detected
// Why this result and this purity source matters
Fisetin is the primary senolytic compound in ReCellence — responsible for identifying and clearing zombie (senescent) cells from tissue. The botanical source matters: Cotinus coggygria stem (European smokebush) is one of the highest natural concentrations of fisetin available, producing a cleaner extraction profile than lower-price sources such as Rhus succedanea that some competitors use. The 98.36% HPLC assay confirms that 983g out of every 1000g is active fisetin — not fillers, not retained flavonoids, not extraction residue. The 280kg batch size reflects serious manufacturing scale. Mercury is not detected at all — the most important heavy metal test for neurological safety. Lead and arsenic are well within the 2ppm limit at 0.40 and 0.42 mg/kg respectively.
HPLC
High-Performance Liquid Chromatography: the gold standard for measuring what percentage of the tested molecule is the active compound. A 96% result means 960mg of active ingredient per 1000g of material. This is the most important number on a COA.
ICP-MS (heavy metals)
Inductively Coupled Plasma Mass Spectrometry: detects heavy metals at parts-per-billion sensitivity. We test for lead, arsenic, cadmium and mercury — the four most toxicologically relevant metals in botanical supplement ingredients.
GC-MS (PAH / ethylene oxide)
Gas Chromatography – Mass Spectrometry: screens for polycyclic aromatic hydrocarbons from combustion processes and ethylene oxide (a sterilization agent that leaves residuals in the final ingredient). Both are not detected in all five compounds.
USP <61> / <62> (microbiology)
United States Pharmacopoeia microbiological testing standards. Run covers total aerobic plate count, yeast and mold, and covers specific pathogens: E. coli, salmonella, and staphylococcus. All are not detected in all five compounds.
Loss on drying
The percentage of the collected that is water or volatile solvent: (raw weight – dried weight) / raw weight. Low loss on drying indicates stable, dry ingredient with minimal residual moisture that could degrade potency over time. All five compounds have excellent loss-on-drying figures.
Total ash
The inorganic residue after complete incineration — primarily minerals. For botanical extracts, elevated ash can reflect elevated mineral content of the plant matrix. The quercetin batch shows 9.14% against a 5.0% specification — we explain this in full above.
Est. 11 yrs · Shaanxi, China
Shaanxi Fairir Biotech is a botanical extract and fine chemical manufacturer based in Xi'an, Shaanxi — the established hub for botanical ingredient production in China. All five COAs on this page are issued by their quality control department, signed and dated, meeting our strict checking criteria, and carry the company's quality control seal. Testing methods used by USP-protocol botanical manufacturers. The HPLC purity testing, ICP-MS heavy metal screening, GC-MS solvent analysis, and USP microbiological panel are standard for FDA-registered supplement ingredient suppliers.